Amlodipine Besylate Api

• Molecular formula:ïC20H25ClN2O5,C6H6O3S
• Molecular weight:ï567.10
• CAS Number:ï111470-99-6
• Application:ïAntihypertensive
• Specification:ïAs per IP/BP/EP/USP

Amlodipine benzenesulfonate is the benzenesulfonate salt of amlodipine. It has a role as a vasodilator agent, a calcium channel blocker and an antihypertensive agent. It contains an amlodipine.
Amlodipine Besylate is the besylate salt of amlodipine,ïa syntheticïdihydropyridine with antihypertensive and antianginal effects.ïAmlodipineïinhibits the influx of extracellularïcalciumïions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. This results in a dilatation of the main coronary and systemic arteries, decreased myocardial contractility, increased blood flow andïoxygenïdelivery to the myocardial tissue, and decreased total peripheral resistance. This agent may also modulate multi-drug resistance (MDR) activity through inhibition of the p-glycoprotein efflux pump.