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Simethicone 100% (Ip/Bp/ Usp)

Price 450.0 INR/ Kilograms

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MOQ : 100 Kilograms

Simethicone 100% (Ip/Bp/ Usp) Specification

EINECS No
232-479-9

Structural Formula
[Si(CH3)2O]n SiO2

Taste
Tasteless

Smell
Odorless

Color
White

Poisonous
Non-poisonous

Ph Level
6.5 - 8.0

Heavy Metal (%)
0.002%

Solubility
Insoluble in water

Shelf Life
36 Months

Storage
Store in tightly closed container in cool, dry place

Molecular Formula
(C2H6OSi)n

Molecular Weight
Variable

HS Code
38249090

Loss on Drying
1.0%

Medicine Name
Simethicone 100%

Chemical Name
Poly(dimethylsiloxane) with silica

CAS No
8050-81-5

Type
Antifoaming Agent

Grade
Pharmaceutical Grade

Usage
Used for treatment of flatulence, bloating, and stomach discomfort

Purity(%)
100%

Appearance
White viscous liquid

Physical Form
Liquid

Silica Content
Approximately 3.0% to 7.0%

Application
Used as anti-foaming agent and digestive aid

Dispersibility
Easily dispersible in water with surfactant

Density
~0.97 g/cm³

Viscosity
2000~3500 cSt

Container type
HDPE Drums or Carboys

Simethicone 100% (Ip/Bp/ Usp) Trade Information

Minimum Order Quantity
100 Kilograms

Supply Ability
1000 Kilograms Per Day

Delivery Time
7 Days

Sample Available
No

Sample Policy
Contact us for information regarding our sample policy

About Simethicone 100% (Ip/Bp/ Usp)

Packaging Type	Bottle
Composition	SIMETHICONE 100 %
Brand Name	DRP
Manufacturer	DRP
Shelf Life	36 Months
Prescription/Non-Prescription	Non-Prescription
Also Gives	PCD Pharma Franchise, Third Party Manufacturing
Minimum Order Quantity	100 Litre

Product Specification

Brand	DRP
Viscosity	2000 CST
Defoaming Performance	15 Seconds maximum at 50 R.P.M.
Compound	Activated Dimethyl Polysioxane
Color	Translucent
Stability	Maximum 5% separation after 15 minutes at 1600 R.P.M
Active	100%
Consistency	Syrupy
Sp. Gravity	0.975 to 0.010 @ 25 Deg C
Refractive Index	1.402 to 1.406 @ 25 Deg C
Free Acid	0.025 to 0.04
Moisture	< 0.5%
Suitable Diluent	Aliphatic, Aromatic and Chlorinated Solvents

Product Description

It is widely used as a versatile Defoamer, in both general industrial applications. In medical and pharmaceutical applications, the requirements for this chemically inert silicone defoamer is unique and exacting.

Wide-Ranging Pharmaceutical Applications

Simethicone 100% meets stringent IP/BP/USP specifications and is widely used as an effective antifoaming agent in the pharmaceutical industry. Its primary function is to alleviate symptoms like bloating and abdominal discomfort caused by excessive gas. This versatile compound is also used in various formulations where efficient gas dispersion is needed and has a high safety profile, making it ideal for digestive products.

Outstanding Physical and Chemical Attributes

With a silica content of approximately 3.0% to 7.0%, Simethicone 100% is characterized by its white, viscous liquid form. It has a viscosity of 2000~3500 cSt, density close to 0.97 g/cm, and is insoluble in water but disperses easily with surfactants. Renowned for its non-toxic, tasteless, and odorless properties, this compound stays stable in storage, provided it is kept in tightly sealed containers in a cool, dry area.

Secure Packaging and Reliable Storage

Delivered in robust HDPE drums or carboys, Simethicone 100% ensures product integrity during transportation and storage. It requires secure storage in a cool, dry place, away from contaminants. The products high stability allows for a shelf life of up to 36 months, provided optimal storage conditions are maintained. Its ease of handling and packaging suits both large-scale manufacturing and pharmaceutical distribution.

FAQs of Simethicone 100% (Ip/Bp/ Usp):

Q: How is Simethicone 100% with silica content used in pharmaceuticals?

A: Simethicone 100% functions as an antifoaming agent in pharmaceutical preparations. It is primarily used to treat flatulence, bloating, and related digestive discomfort by reducing surface tension and collapsing gas bubbles in the gastrointestinal tract. It can be formulated into tablets, capsules, or suspensions, often in combination with surfactants for better dispersibility.

Q: What are the main benefits of using Simethicone 100% as a digestive aid?

A: The primary benefits of Simethicone 100% include rapid relief from gas-related symptoms such as bloating, abdominal pain, and discomfort. It acts locally in the stomach and intestines, is non-poisonous, tasteless, and is compatible with most pharmaceuticals, ensuring patient safety and efficacy.

Q: Where should Simethicone 100% be stored to maintain its effectiveness?

A: Simethicone 100% should be stored in tightly closed containers, preferably HDPE drums or carboys, in a cool, dry place. Avoid exposure to moisture and extreme temperatures to preserve its physical and chemical stability throughout its 36-month shelf life.

Q: When is it appropriate to use Simethicone 100% in formulations?

A: Simethicone 100% is suitable for use during the development of pharmaceutical products designed to alleviate symptoms of gas accumulation, flatulence, and bloating. It is often added during the blending stage of manufacturing, especially in liquid or semi-solid preparations where antifoaming properties are required.

Q: What is the process for dispersing Simethicone 100% in water-based applications?

A: Simethicone 100% is insoluble in water; however, it can be easily dispersed in aqueous solutions by incorporating suitable surfactants. This process is common in pharmaceutical manufacturing for producing uniform suspensions or emulsions required for effective delivery in oral or topical dosage forms.

Q: Is Simethicone 100% safe and non-toxic for human consumption?

A: Yes, Simethicone 100% is classified as non-poisonous and is widely recognized as safe for pharmaceutical use. It is tasteless, odorless, and free of heavy metals above safety thresholds, making it suitable for regular and therapeutic use under recommended guidelines.

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