Aceclofenac API

Specifications

CAS No:89796-99-6

Molecular Weight: 354.19

Specification: EP4/5/6

Package and Storage:

25kg/drum, 10kg/drum, inner package: two layers of PE bag,

outer package: fibre drum.

Stored in a cool, dry and ventilated place. Retest Period: 2 years.

Appearance: White or almost white crystalline powder.

Assay: 99.0-101.0%

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TypeïAntibiotic and Antimicrobial Agents

Use:Anti-inflammatory; analgesic

Purity:99%

Quality:BP2002/BP2010

Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studiesï2,3,5. Aceclofenac potently inhibits the cyclo-oxygenase enzyme (COX) that is involved in the synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and fever. Aceclofenac belongs to BCS Class II as it possesses poor aqueous solubilityï2. It displays high permeability to penetrate into synovial joints where in patients with osteoarthritis and related conditions, the loss of articular cartilage in the area causes joint pain, tenderness, stiffness, crepitus, and local inflammationï1. Aceclofenac is also reported to be effective in other painful conditions such as dental and gynaecological conditions.